Yb(OTf)₃-Mediated Regioselective Hydroamination of Ynamides with Anilines and p-Toluenesulfonamide

Abstract

A rare-earth salt Yb(OTf)₃-catalyzed regioselective hydroamination of ynamides with anilines and p-toluenesulfonamide has been developed. This protocol provided facile access to a diverse range of amidines with good functional group tolerance in moderate to high yields.

Key words

rare-earth salts - hydroamination - ynamides - amidines - amide

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